International nonproprietary name


Pharmacological group

Macrolide antibiotic

Active substance

Oleandomycin phosphate

Chemical formula



White or white with yellowish shade crystalline powder, hygroscopic, stable to light.

Molecular mass



775 μg/mg

Pharmacological action

Antibacterial, bacteriostatic. It inhibits synthesis of microbial proteins at level of ribosomes (breaks formation of peptide bonds and growth of polypeptide chains). It has bacteriostatic action against Gram-positive (Staphylococcus spp., producing and not producing penicillinase; Streptococcus spp., including S. pneumoniae; Bacillus anthracis, Corynebacterium diphtheriae) and some Gram-negative microorganisms (Neisseria gonorrhoeae, Haemophillus influenzae, Bordetella pertussis, Brucella spp., Legionella spp.), and also Mycoplasma spp., Chlamydia spp., Treponema spp., Rickettsia spp. It is ineffective against Escherichia coli and other Gram-negative Enterobacteriaceae.

Not cumulated. It is well adsorbed after oral administration, quickly penetrates into many organs and biological fluids.

The use of drugs based on 'Oleandomycin'

Pneumonia, pleuritis, abscess of lungs, pleura empyema, bronchiectasis, tonsillitis, otitis, scarlatina, diphtheria, pertussis, trachoma, protracted endocarditis, meningitis, sepsis (staphylococcal, streptococcal, pneumococcal), osteomyelitis, furunculosis, gonorrhea, coloenteritis, infections of urinary and cholic paths (if liver parenchyma is not affected) and other diseases caused by microorganisms sensitive to oleandomycin, including resistant to other antibiotics (especially to penicillins).



Two-layer polyethylene bags 0,5; 1; 2,5; 4,0; 5,0; 8,0 kg into paper bags.

Drugs produced OJSC «BIOSINTEZ», based on the substance 'Oleandomycin'

-Oletetrin tablets, coated 47,5 mg + 77,5 mg, 20 pcs

Storage conditions

In a dry place, at a temperature of not more than 20°C.

Expiration date

3 years